HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenesulfonyl chloride → HCID 68183202, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenesulfonyl chloride | HCID 7369 | — |
| Reactant | HCID 68183301 | HCID 68183301 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 68183202 | HCID 68183202 | 66% |
Reaction Steps
In a similar fashion using route 14 general procedure 26, 8-Amino-quinoline-4-carboxylic acid methyl ester 489 (56 mg, 0.27 mmol), benzenesulfonyl chloride (54 mg, 0.30 mmol) and pyridine (5 ml) gave the title compound (61 mg, 64%) after purification by column chromatography with DCM/EtOAc (90:10 as the eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-294d28fc18df4fe58b4c4ccb73fc4e1c |
| Source note | uspto-grants-2015_08 |