HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-Aminoquinoline → HCID 51238102, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-Aminoquinoline | HCID 11359 | — |
| Reactant | 3-Methylbenzenesulphonyl chloride | HCID 2734595 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Product | HCID 51238102 | HCID 51238102 | 64.5% |
Reaction Steps
In the similar fashion using route 14 general procedure 27, 8-aminoquinoline (200 mg, 1.38 mmol), m-toluenesulfonyl chloride (260 mg, 1.3 mmol) and DMAP (cat.) gave the title compound (250 mg, 60%) after purification by column chromatography with DCM as the eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-add3edd2e4e3457eabf776c28115232d |
| Source note | uspto-grants-2015_08 |