HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-Aminoquinoline → HCID 60163842, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-Aminoquinoline | HCID 11359 | — |
| Reactant | 2,4,6-Trichlorobenzenesulfonyl chloride | HCID 521335 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Product | HCID 60163842 | HCID 60163842 | 76% |
Reaction Steps
In the similar fashion using route 14 general procedure 27, 8-aminoquinoline (100 mg, 0.69 mmol), 2,4,6 trichlorobenzenesulfonyl chloride (280 mg, 1.03 mmol) and DMAP (cat.) gave the title compound (200 mg, 76%) after purification by column chromatography with DCM as the eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-62c7f5227d764be6a40c6a4259d424cd |
| Source note | uspto-grants-2015_08 |