HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-Aminoquinoline → HCID 68183305, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-Aminoquinoline | HCID 11359 | — |
| Reactant | 3-Chloro-2-methylbenzenesulfonyl chloride | HCID 522734 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Product | HCID 68183305 | HCID 68183305 | 65% |
Reaction Steps
In a similar fashion using route 14 general procedure 27, 8-aminoquinoline (100 mg, 0.7 mmol), 2-methyl-3-chlorobenzenesulfonyl chloride (180 mg, 0.8 mmol) and DMAP (cat.) gave the title compound (150 mg, 65%) after purification by column chromatography with DCM as the eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-5d118b59f2424e1a97fce5db7b3a1a57 |
| Source note | uspto-grants-2015_08 |