HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-Aminoquinoline → HCID 68183207, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-Aminoquinoline | HCID 11359 | — |
| Reactant | 2-Chloro-6-methylbenzene-1-sulfonyl chloride | HCID 15725370 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Product | HCID 68183207 | HCID 68183207 | 48% |
Reaction Steps
In a similar fashion using route 14 general procedure 27, using 8-aminoquinoline (100 mg, 0.69 mmol), 2-chloro-6-methylbenzenesulfonyl chloride (230 mg, 1.04 mmol) and DMAP (cat.) gave the title compound (110 mg, 48%) after purification by column chromatography with DCM as the eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-27bb3150dda24e81b1e79b8e4e7c6187 |
| Source note | uspto-grants-2015_08 |