HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenesulfonyl chloride → HCID 68183244, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenesulfonyl chloride | HCID 7369 | — |
| Reactant | HCID 68183413 | HCID 68183413 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Product | HCID 68183244 | HCID 68183244 | 40% |
Reaction Steps
In a similar fashion using route 14 general procedure 27, 7-isopropylquinolin-8-amine (Intermediate 62) (150 mg, 0.81 mmol), bezenesulfonyl chloride (170 mg, 1.0 mmol) and DMAP (cat.) gave the title compound (105 mg, 40%) after purification by column chromatography with n-hexane/EtOAc (17:3-4:1) gradient elution.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-332268cedd4a437a992592294c0f0a2e |
| Source note | uspto-grants-2015_08 |