HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenesulfonyl chloride → HCID 68183379, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenesulfonyl chloride | HCID 7369 | — |
| Reactant | HCID 68183445 | HCID 68183445 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Product | HCID 68183379 | HCID 68183379 | 15.2% |
Reaction Steps
In a similar fashion using route 14 general procedure 27, 7-ethylquinolin-8-amine (Intermediate 63) (144 mg, 0.84 mmol), benzenesulfonyl chloride (170 mg, 1.01 mmol) and DMAP (cat.) gave the title compound (40 mg, 15%) after purification by column chromatography with n-hexane/ EtOAc (17:3) as the eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-31943ef17f244900856096723634c77f |
| Source note | uspto-grants-2015_08 |