HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenesulfonyl chloride → HCID 60164090, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenesulfonyl chloride | HCID 7369 | — |
| Reactant | 7-Methoxyquinolin-8-amine | HCID 12849813 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Product | HCID 60164090 | HCID 60164090 | 33.3% |
Reaction Steps
In a similar fashion using route 14 general procedure 27, 7-methoxyquinolin-8-amine (Intermediate 64) (150 mg, 0.86 mmol), benzenesulfonyl chloride (130 μl, 1.03 mmol) and DMAP (cat.) gave the title compound (90 mg, 33%) after recrystallisation from DCM/n-pentane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-96ded5af54004819b6c23cb14aaf8fcd |
| Source note | uspto-grants-2015_08 |