Sodium hydrogen sulphide → HCID 178418618, compound

HRID 5135Notes

Reaction equation

HRID 5135 reaction equation
S.[Na].[N+:3]([C:6]1[CH:15]=[CH:14][C:9]2[N:10]=[C:11]([SH:13])[S:12][C:8]=2[CH:7]=1)([O-])=O>O>[NH2:3][C:6]1[CH:15]=[CH:14][C:9]2[N:10]=[C:11]([SH:13])[S:12][C:8]=2[CH:7]=1

Participants

4

Reactant 2

HCID 86586439Sodium hydrogen sulphideHCID 178418579HCID 178418579, compound

Product 1

HCID 178418618HCID 178418618, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
20 °C

Procedure

132 Parts of sodium hydrogen sulphide was dissolved in 400 parts of water, and stirred at 20° C. 53 Parts of 6-nitro-2-mercaptobenzothiazole, prepared as described previously herein, was added over 10 minutes; the reaction mixture was then heated to 110° C., and stirred whilst boiling the mixture under reflux conditions. After four hours boiling, the mixture was cooled to between 0° and 5° C. and stirred for one hour. The product, 6-amino-2-mercaptobenzothiazole (30.3 parts), was isolated by filtration, washed sparingly with cold water and dried at 60° C. for 24 hours.

Workup

  1. additionwas added over 10 minutes
  2. temperaturethe reaction mixture was then heated to 110° C.
  3. stirringstirred whilst
  4. temperaturethe mixture was cooled to between 0° and 5° C.
  5. stirringstirred for one hour

Sources & evidence

ORD record
ord-e195c176d6b849b682dd3bfd3a2e2e17
Source dataset
uspto-grants-1993_09
Patent number
US05243047

Reaction notes

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