HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-Aminoquinoline → 4-Fluoro-2-nitro-N-quinolin-8-yl-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-Aminoquinoline | HCID 11359 | — |
| Reactant | 4-Fluoro-2-nitrobenzene-1-sulfonyl chloride | HCID 2759046 | — |
| Product | 4-Fluoro-2-nitro-N-quinolin-8-yl-benzenesulfonamide | HCID 16759924 | 105.6% |
Reaction Steps
In a similar fashion using route 14 general procedure 26, 8-aminoquinoline (500 mg, 3 mmol) and 2-nitro-4-fluorobenzenesulfonyl chloride (Intermediate 220) (914 mg, 4 mmol) gave the title compound (1.10 g, 91%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-d9c7fef85bcf44ffa3b46e8243797e03 |
| Source note | uspto-grants-2015_08 |