HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Nitrobenzenesulfonyl chloride → N-(2-Methyl-quinolin-8-yl)-2-nitro-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Nitrobenzenesulfonyl chloride | HCID 15540 | — |
| Reactant | 2-Methyl-8-aminoquinoline | HCID 140457 | — |
| Product | N-(2-Methyl-quinolin-8-yl)-2-nitro-benzenesulfonamide | HCID 16759518 | 47% |
Reaction Steps
In a similar fashion using route 14 general procedure 26, 2-methyl-quinolin-8-ylamine (Intermediate 22) (417 mg, 2.64 mmol) and 2-nitrobenzensulfonyl chloride (643 mg, 2.64 mmol) gave the title compound (423 mg, 47%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-c57e48eb75884d9cac5cdf631bac96a5 |
| Source note | uspto-grants-2015_08 |