反应详情

In a similar fashion using route 14 general procedure 26, 6-fluoroquinolin-8-ylamine (Intermediate 48) (320 mg, 1.97 mmol), 2-nitro-benzenesulfonyl chloride (523 mg, 2.37 mmol), pyridine (2 ml) for 16 h gave the title compound (520 mg, 76%) which was used in the next step without further purification.

1. customfor 16 h