HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Methoxy-8-quinolinamine → N-(5-methoxyquinolin-8-yl)-2-nitrobenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Methoxy-8-quinolinamine | HCID 7023 | — |
| Reactant | 2-Nitrobenzenesulfonyl chloride | HCID 15540 | — |
| Reactant | 5-Methoxyquinolin-8-amine | HCID 777110 | — |
| Product | N-(5-methoxyquinolin-8-yl)-2-nitrobenzenesulfonamide | HCID 68183469 | 64% |
Reaction Steps
In a similar fashion using route 14 general procedure 27, 6-methoxyquinolin-8-amine (Intermediate 67) (350 mg, 2.01 mmol) and 2-nitrobenzenesulfonyl chloride (533 mg, 2.41 mmol) gave the title compound (460 mg, 64%) after purification by column chromatography with DCM as the eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-baa967f0756c4a738e50b737b426a6ae |
| Source note | uspto-grants-2015_08 |