HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous chloride dihydrate → 2-Amino-4-fluoro-N-quinolin-8-yl-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous chloride dihydrate | HCID 61436 | — |
| Reactant | 4-Fluoro-2-nitro-N-quinolin-8-yl-benzenesulfonamide | HCID 16759924 | — |
| Product | 2-Amino-4-fluoro-N-quinolin-8-yl-benzenesulfonamide | HCID 16759931 | 90% |
Reaction Steps
In a similar fashion using route 15 general procedure 29, 4-fluoro-2-nitro-N-quinolin-8-yl-benzenesulfonamide (Example Compound 30) (1.1 g, 3.17 mmol) and tin (II) chloride dihydrate (4.29 g, 19 mmol) gave the title compound (900 mg, 90%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-dbaeb1e2bee04c78a639f0f455fec7e2 |
| Source note | uspto-grants-2015_08 |