HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous chloride dihydrate → 2-Amino-N-quinolin-8-yl-4-trifluoromethyl-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous chloride dihydrate | HCID 61436 | — |
| Reactant | 2-Nitro-N-quinolin-8-yl-4-trifluoromethyl-benzenesulfonamide | HCID 16759914 | — |
| Product | 2-Amino-N-quinolin-8-yl-4-trifluoromethyl-benzenesulfonamide | HCID 16759548 | 71% |
Reaction Steps
In a similar fashion using route 15 general procedure 29, 2-nitro-N-quinolin-8-yl-4-trifluoromethyl-benzenesulfonamide (Example Compound 32) (1.22 g, 3.07 mmol) and tin (II) chloride dihydrate (3.46 g, 15.4 mmol) gave the title compound (797 mg, 71%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-3de100d18c604be5856535ed362f52e3 |
| Source note | uspto-grants-2015_08 |