HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous Chloride → 2-Amino-4-methoxy-N-quinolin-8-yl-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous Chloride | HCID 24479 | — |
| Reactant | 4-Methoxy-2-nitro-N-quinolin-8-yl-benzenesulfonamide | HCID 16759547 | — |
| Catalyst | Hydrochloric Acid | HCID 313 | — |
| Product | 2-Amino-4-methoxy-N-quinolin-8-yl-benzenesulfonamide | HCID 16759517 | 56.9% |
Reaction Steps
In the similar fashion using route 1 general procedure 4, 4-methoxy-2-nitro-N-quinolin-8-yl-benzenesulfonamide (Example Compound 34) (600 mg, 1.6 mmol), tin (II) chloride (950 mg, 5.0 mmol) and 6N HCl (2 drops) gave the title compound (300 mg, 54%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-162ba09d5d6c49eb97df3603f318a884 |
| Source note | uspto-grants-2015_08 |