Stannous Chloride → HCID 68183511, compound

Participants

Reaction Steps

In a similar fashion using route 1 general procedure 4, N-(5-chloro-quinolin-8-yl)-4,5-difluoro-2-nitro-benzenesulfonamide (Intermediate 257) (125 mg, 0.31 mmol), SnCl2 (238 mg, 1.25 mmol), 6N HCl (3 drops) and EtOH (3 ml) for 3.5 h at 85° C. gave the title compound (95 mg, 72%) which was used in the next step without further purification.

Provenance & Evidence