Stannous Chloride → HCID 68183293, compound

Participants

Reaction Steps

In a similar fashion using route 1 general procedure 4, 8-(2-nitro-benzenesulfonylamino)-quinoline-4-carboxylic acid methyl ester (Intermediate 260) (0.62 g, 1.6 mmol), SnCl2 (1.3 g, 6.4 mmol), 6N HCl (2 drops) and MeOH (15 ml) at 80° C. for 48 h gave the title compound (270 mg, 50%) which was used in the next step without further purification.

Provenance & Evidence