HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous Chloride → HCID 68183268, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous Chloride | HCID 24479 | — |
| Reactant | HCID 68183322 | HCID 68183322 | — |
| Catalyst | Hydrochloric Acid | HCID 313 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 68183268 | HCID 68183268 | 71.9% |
Reaction Steps
In a similar fashion using route 1 general procedure 4, 5-methoxy-2-nitro-N-quinolin-8-yl-benzenesulfonamide (Intermediate 264) (690 mg, 1.9 mmol), SnCl2 (1.45 g, 7.68 mmol), 6N HCl (2 drops) and EtOH (12 ml) at 85° C. for 6 h gave the title compound (450 mg, 71%) which was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-2612f2e5eed44b3fb9d7378ed9bdf1ad |
| Source note | uspto-grants-2015_08 |