HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous Chloride → HCID 68183359, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous Chloride | HCID 24479 | — |
| Reactant | HCID 60531925 | HCID 60531925 | — |
| Catalyst | Hydrochloric Acid | HCID 313 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 68183359 | HCID 68183359 | 39.3% |
Reaction Steps
In a similar fashion using route 1 general procedure 4, 2-methyl-6-nitro-N-quinolin-8-yl-benzenesulfonamide (Intermediate 268) (1.5 g, 4.3 mmol), SnCl2 (3.3 g, 17.5 mmol), 6N HCl (5 drops) and EtOH (15 ml) gave the title compound (530 mg, 38%), after purification by column chromatography with DCM/MeOH (99:1) as the eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-713507a7062748f69e3b6f2f9894ee4f |
| Source note | uspto-grants-2015_08 |