HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous Chloride → 2-Amino-N-(5-methylquinolin-8-yl)-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous Chloride | HCID 24479 | — |
| Reactant | N-(5-methylquinolin-8-yl)-2-nitrobenzenesulfonamide | HCID 68183358 | — |
| Catalyst | Hydrochloric Acid | HCID 313 | — |
| Product | 2-Amino-N-(5-methylquinolin-8-yl)-benzenesulfonamide | HCID 68183462 | 58% |
Reaction Steps
In a similar fashion using route 1 general procedure 4, N-(5-methylquinolin-8-yl)-2-nitrobenzenesulfonamide (Intermediate 159) (830 mg, 2.42 mmol), tin (II) chloride (1.83 g, 9.68 mmol) and 6 N HCl (3 drops) gave the title compound (430 mg, 58%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-97a7912d52484f249f37f9ad6cc87750 |
| Source note | uspto-grants-2015_08 |