Acetic Acid → HCID 60164545, compound

Participants

Reaction Steps

In a similar fashion using route 16 general procedure 61, 2-amino-N-(5-chloro-quinolin-8-yl)-4-methanesulfonyl-benzenesulfonamide (Intermediate 274) (205 mg, 0.5 mmol), t-butyl nitrite (0.09 ml, 0.75 mmol), AcOH (4 ml) and THF (4 ml) gave the title compound (22 mg, 16%) after purification by column chromatography with DCM as the eluent.

Provenance & Evidence