Acetic Acid → HCID 24858338, compound

Participants

Reaction Steps

In a similar fashion using route 16 general procedure 61, 2-amino-5-methoxy-N-quinolin-8-yl-benzenesulfonamide (Intermediate 293) (450 mg, 1.36 mmol), t-butyl nitrite (0.24 ml, 2.04 mmol), AcOH (4.5 ml) and THF (4.5 ml) gave the title compound (19 mg, 4%) after purification by column chromatography with DCM/MeOH (99.7:0.3) as the eluent.

Provenance & Evidence