(8-Nitro-quinolin-7-ylmethyl)-phenyl-amine → 7-Phenylaminomethyl-quinolin-8-ylamine

Participants

Reaction Steps

Palladium on Carbon (10%, 36 mg) was added to a solution of (8-nitro-quinolin-7-ylmethyl)-phenyl-amine (Intermediate 205) (478 mg, 1.69 mmol) in EtOH (10 ml) and the mixture was stirred under an atmosphere of hydrogen for 4 h. The mixture was diluted with MeOH (40 ml), filtered through celite and the filtrate was concentrated in vacuo to give the title compound (428 mg, 89%).

Provenance & Evidence