HuagongsheHuagongshe Chemistry Print Report · For research reference only
C-(8-nitroquinolin-7-yl)-methylamine dihydrochloride → HCID 68183296, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | C-(8-nitroquinolin-7-yl)-methylamine dihydrochloride | HCID 68183387 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 68183296 | HCID 68183296 | 31% |
Reaction Steps
Palladium on Carbon (5%, 25 mg) was added to a solution of C-(8-nitroquinolin-7-yl)-methylamine dihydrochloride (Intermediate 210) (180 mg, 1.09 mmol) in EtOH (10 ml) and the mixture was stirred under an atmosphere of hydrogen for 5 h. The mixture was diluted with MeOH (10 ml), filtered through celite and the filtrate was concentrated in vacuo to give the title compound (5 mg, 31%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-eed176ab1187478095a49df743ce12a8 |
| Source note | uspto-grants-2015_08 |