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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 513651Generated: October 30, 2026

C-(8-nitroquinolin-7-yl)-methylamine dihydrochloride → HCID 68183296, compound

https://huagongshe.com/reaction/513651

Reaction equation

Participants

RoleNameHCIDCharge
ReactantC-(8-nitroquinolin-7-yl)-methylamine dihydrochlorideHCID 68183387—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
SolventMethanolHCID 887—
ProductHCID 68183296HCID 6818329631%

Reaction Steps

Palladium on Carbon (5%, 25 mg) was added to a solution of C-(8-nitroquinolin-7-yl)-methylamine dihydrochloride (Intermediate 210) (180 mg, 1.09 mmol) in EtOH (10 ml) and the mixture was stirred under an atmosphere of hydrogen for 5 h. The mixture was diluted with MeOH (10 ml), filtered through celite and the filtrate was concentrated in vacuo to give the title compound (5 mg, 31%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09102688B2
Source datasetuspto-grants-2015_08
ORD IDord-eed176ab1187478095a49df743ce12a8
Source noteuspto-grants-2015_08