HCID 68183215, compound → HCID 68183071, compound

Participants

Reaction Steps

PCC (667 mg, 3.1 mmol) was added to a solution of (4-fluoro-2-methyl-phenyl)-(8-nitro-quinolin-7-yl)-methanol (Intermediate 350) (690 mg, 2.21 mmol) in DCM (700 ml) and the mixture was stirred at room temperature for 2 h. The mixture was filtered through celite and the filtrate was concentrated in vacuo. The crude residue was purified by column chromatography with n-hexane/DCM (30:70) as the eluent to give the title compound (600 mg, 87%).

Provenance & Evidence