HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(8-Amino-quinolin-7-yl)-propan-1-ol → 1-(8-Amino-quinolin-7-yl)-propan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(8-Amino-quinolin-7-yl)-propan-1-ol | HCID 68183160 | — |
| Catalyst | Manganese dioxide | HCID 14801 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1-(8-Amino-quinolin-7-yl)-propan-1-one | HCID 68183302 | 80.7% |
Reaction Steps
In a similar fashion using route 27 general procedure 68, 1-(8-amino-quinolin-7-yl)-propan-1-ol 408 (1.0 g, 4.95 mmol), MnO2 powder (4.3 g, 49.5 mmol) and DCM (10 ml) gave the title compound (800 mg, 80%) which was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-eb960c037c2942f39a8178ea2e689ace |
| Source note | uspto-grants-2015_08 |