Sodium borohydride → HCID 68183345, compound

Participants

Reaction Steps

In a similar fashion using route 27 general procedure 70, (8-amino-quinolin-7-yl)-(3-[1,3]dioxolan-2-yl-4-fluoro-phenyl)-methanone 420 (500 mg, 1.48 mmol), N-methylsulfamoyl chloride 213 (574 mg, 4.43 mmol) and NaBH4 (56 mg, 1.48 mmol) in pyridine (10 ml) gave the title compound (442 mg, 72%) after purification by column chromatography with heptane/EtOAc (50:50) as the eluent.

Provenance & Evidence