N,N-Dimethylethylenediamine → HCID 68183349, compound

Participants

Reaction Steps

Sodium triacetoxyborohydride (40 mg, 0.19 mmol) was added to a solution of 2-fluoro-5-(2-methyl-3,3-dioxo-1,2,3,4-tetrahydro-3λ*6*-thia-2,4,5-triaza-phenanthren-1-yl)-benzaldehyde 422 (50 mg, 0.13 mmol) and N,N-dimethylethane-1,2-diamine (12.9 μl, 0.16 mmol) in DCE (2 ml) and the mixture was stirred at room temperature for 18 h. The reaction was quenched with sat. NaHCO3 solution (1 ml) and the mixture was extracted with EtOAc (5 ml). The organic phase was concentrated in vacuo. The crude residue was triturated from chloroform/MeOH to give the title compound (20 mg, 34%).

Provenance & Evidence