HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl mercaptan → HCID 22923306, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl mercaptan | HCID 7509 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Chloropyrazine | HCID 73277 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 22923306 | HCID 22923306 | 45.6% |
Reaction Steps
In a similar fashion using route 38 general procedure 92, 2-chloropyrazine (1 g, 8.73 mmol), K2CO3 (1.80 g 13.1 mmol), benzylmercaptan (1.62 g 13.1 mmol) and DMSO (8 ml) at 150° C. for 4 h in sealed tube gave the title compound (805 mg, 45%) after purification by column chromatography with n-hexane/EtOAc (97:3) as the eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-1e1048cf0c164c2ea2a126992ef7c09f |
| Source note | uspto-grants-2015_08 |