HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → p-Nitrotoluene-m-sulfonic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium Sulfite | HCID 24437 | — |
| Reactant | Benzene, 2-fluoro-4-methyl-1-nitro- | HCID 67966 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | p-Nitrotoluene-m-sulfonic acid | HCID 12332055 | 249.8% |
Reaction Steps
In a similar fashion using route 39 general procedure 95, 2-fluoro-4-methyl-1-nitrobenzene (2 g, 12.9 mmol) in EtOH (24 ml) and Na2SO3 (2.04 g, 16.0 mmol) in EtOH:water (40 ml: 32 ml) at 70° C. for 14 h gave the title compound (7 g) which was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-45c3b4e44c8f4e3ea4ea73ca7dd7cc77 |
| Source note | uspto-grants-2015_08 |