HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2-Nitro-p-toluenesulphonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-Nitrotoluene-4-sulfonic acid | HCID 2762516 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-Nitro-p-toluenesulphonyl chloride | HCID 104689 | — |
Reaction Steps
In a similar fashion using route 39 general procedure 96, 4-methyl-2-nitro-benzenesulfonic acid 448 (6.2 g, Salt form), SOCl2 (15 ml) and DMF (0.28 ml) gave the title compound (3.10 g) which was used in the next step without further purification. The structure was confirmed by 1H NMR.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-cf6c8fc04a2f4fd4a802f53a090aa017 |
| Source note | uspto-grants-2015_08 |