HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2-Methyl-6-nitrobenzene-1-sulfonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 12215944 | HCID 12215944 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-Methyl-6-nitrobenzene-1-sulfonyl chloride | HCID 12215942 | — |
Reaction Steps
In a similar fashion using route 39 general procedure 96, 2-methyl-6-nitro-benzenesulfonic acid 451 (7.2 g crude), SOCl2 (16 ml) and DMF (0.35 ml) at 90° C. for 3 h gave the title compound (3.5 g) which was used in the next step without further purification. The structure was confirmed by 1H NMR.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-f440671f4f114378bb541b6188becbed |
| Source note | uspto-grants-2015_08 |