反应详情

温度

100 °C

KOH (2.69 g, 47.9 mmol) was added to a solution of 5-chloro-8-nitro-quinoline 27 (1.0 g, 4.79 mmol) in EtOH (20 ml) and water (30 ml) and the mixture was heated at 100° C. for 2 h. The reaction mixture was cooled in the fridge for 18 h and the resulting crystals were collected by filtration and dried to give the title compound (616 mg, 68%).

1. temperatureThe reaction mixture was cooled in the fridge for 18 h
2. filtrationthe resulting crystals were collected by filtration
3. customdried