HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous Chloride → 2-Amino-N-(5-benzyloxy-quinolin-8-yl)-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous Chloride | HCID 24479 | — |
| Reactant | N-(5-Benzyloxy-quinolin-8-yl)-2-nitro-benzenesulfonamide | HCID 68183366 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Amino-N-(5-benzyloxy-quinolin-8-yl)-benzenesulfonamide | HCID 68183505 | 86.4% |
Reaction Steps
In a similar fashion using route 19 general procedure 29, N-(5-benzyloxy-quinolin-8-yl)-2-nitro-benzenesulfonamide 566 (519 mg, 1.19 mmol), SnCl2 (1.08 g, 4.77 mmol), and EtOH (10 ml) gave the title compound (417 mg, 86%) which was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-d4c270105af146e7a60ef5af951b4aab |
| Source note | uspto-grants-2015_08 |