HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous Chloride → 8-Amino-5-morpholinoquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous Chloride | HCID 24479 | — |
| Reactant | 5-Morpholin-4-yl-8-nitro-quinoline | HCID 3135677 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 8-Amino-5-morpholinoquinoline | HCID 14501162 | 87.2% |
Reaction Steps
In a similar fashion using route 19 general procedure 29, 5-morpholin-4-yl-8-nitro-quinoline 580 (200 mg, 0.77 mmol), SnCl2 (696 mg, 3.09 mmol) and EtOH (5 ml) gave the title compound (154 mg, 87%) which was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-db868241d5c44a93bec2bb8ebe9094c2 |
| Source note | uspto-grants-2015_08 |