HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous Chloride → 2-Amino-N-(5-morpholin-4-yl-quinolin-8-yl)-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous Chloride | HCID 24479 | — |
| Reactant | N-(5-Morpholin-4-yl-quinolin-8-yl)-2-nitro-benzenesulfonamide | HCID 68182942 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Amino-N-(5-morpholin-4-yl-quinolin-8-yl)-benzenesulfonamide | HCID 68183436 | 75.5% |
Reaction Steps
In a similar fashion using route 19 general procedure 29, N-(5-morpholin-4-yl-quinolin-8-yl)-2-nitro-benzenesulfonamide 582 (216 mg, 0.52 mmol), SnCl2 (470 mg, 2.09 mmol), and EtOH (5 ml) gave the title compound (151 mg, 75%) which was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09102688B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-bbff8501bbe04086859b19a11f982f38 |
| Source note | uspto-grants-2015_08 |