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HRID514131

反应详情

EQUATION

反应方程式

HRID 514131 的结构方程式

REACTANTS

反应物

2
结构：C1COCCN1
HCID8083

Morpholine

C4H9NO

结构：Cc1c(C(OC(C)(C)C)C(=O)O)c(-c2ccc(Cl)cc2)c2ccccc2c1CN(C)C
HCID67126197

未命名化合物

PRODUCTS

生成物

1
结构：Cc1c(C(OC(C)(C)C)C(=O)O)c(-c2ccc(Cl)cc2)c2ccccc2c1CN1CCOCC1
HCID67126196

未命名化合物

PROCEDURE

实验过程

2-tert-Butoxy-2-(1-(4-chlorophenyl)-3-methyl-4-(morpholinomethyl)naphthalen-2-yl)acetic acid (134) was prepared in a manner similar to 2-tert-butoxy-2-(1-(4-chlorophenyl)-4-((dimethylamino)methyl)-3-methylnaphthalen-2-yl)acetic acid of Example 131, except using morpholine in the reductive amination step. LCMS-ESI+ (m/z): [M+H]+ calcd for C28H33ClNO4: 482.2; Found: 482.0.