HCID 5461450, compound → HCID 178510221, compound

HRID 514335Notes

Reaction equation

HRID 514335 reaction equation
[NH:1]([C:3]1[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=1)[NH2:2].O=[C:12]([CH2:18][O:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)[CH2:13][C:14](OC)=[O:15]>>[OH:15][C:14]1[N:1]([C:3]2[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=2)[N:2]=[C:12]([CH2:18][O:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH:13]=1

Participants

3

Reactant 2

HCID 5461450HCID 5461450, compoundHCID 201187142-Hydrazinylpyridine-4-carbonitrile

Product 1

HCID 178510221HCID 178510221, compoundYield 58%

Procedure

The title compound was prepared in 58% yield from 2-hydrazinylpyridine-4-carbonitrile (PREPARATION 2) and methyl 3-oxo-4-phenoxybutanoate according to the procedure for the preparation of Example 3, part A. [M+H] Calc'd for C16H12N4O2, 293. Found, 293.

Sources & evidence

ORD record
ord-0a26c8d0a9374efea9263722b951c881
Source dataset
uspto-grants-2015_08
Patent number
US09107916B2

Reaction notes

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