HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methylacetophenone → (2E)-3-(Dimethylamino)-1-(3-methylphenyl)prop-2-en-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methylacetophenone | HCID 11455 | — |
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Product | (2E)-3-(Dimethylamino)-1-(3-methylphenyl)prop-2-en-1-one | HCID 19807213 | 35% |
Reaction Steps
The title compound was prepared in 35% yield from 1-(3-methylphenyl)ethanone and DMF-DMA according to the procedure for the preparation of Example 12, part A. 1H NMR (400 MHz, CDCl3): δ 2.39 (3H, s), 2.79-3.11 (6H, m), 5.70 (1H, d, J=12.4 Hz), 7.24-7.31 (2H, m), 7.66-7.71 (2H, m), 7.78 (1H, d, J=12.4 Hz).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09107916B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-2873005cdbc848fb862feddeea823865 |
| Source note | uspto-grants-2015_08 |