HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxyacetophenone → (2E)-3-(dimethylamino)-1-(3-methoxyphenyl)prop-2-en-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxyacetophenone | HCID 11460 | — |
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Product | (2E)-3-(dimethylamino)-1-(3-methoxyphenyl)prop-2-en-1-one | HCID 12233520 | 89% |
Reaction Steps
The title compound was prepared in 89% yield from 1-(3-methoxyphenyl)ethanone and DMF-DMA according to the procedure for the preparation of Example 12, part A. 1H NMR (400 MHz, CDCl3): δ 2.94 (3H, s), 3.13 (3H, s), 3.85 (3H, s), 7.69 (1H, d, J=12.4 Hz), 6.98-7.01 (1H, m), 7.29-7.46 (3H, m), 7.79 (1H, d, J=12.4 Hz).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09107916B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-457ed53fcaa4415e8884a6e1aabfbfab |
| Source note | uspto-grants-2015_08 |