HCID 1488370, compound → HCID 86725505, compound

HRID 514376Notes

Reaction equation

HRID 514376 reaction equation
CN(C)/[CH:3]=[C:4](\[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)/[C:5](=O)[CH3:6].[NH:15]([C:17]1[CH:18]=[C:19]([CH:22]=[CH:23][N:24]=1)[C:20]#[N:21])[NH2:16]>>[CH3:6][C:5]1[N:15]([C:17]2[CH:18]=[C:19]([C:20]#[N:21])[CH:22]=[CH:23][N:24]=2)[N:16]=[CH:3][C:4]=1[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 1488370HCID 1488370, compoundHCID 201187142-Hydrazinylpyridine-4-carbonitrile

Product 1

HCID 86725505HCID 86725505, compoundYield 34%

Procedure

The title compound was prepared in 34% yield from (3E)-4-(dimethylamino)-3-phenylbut-3-en-2-one and 2-hydrazinylisonicotinonitrile (PREPARATION 2) according to the procedure for the preparation of Example 28, part D. [M+H] Calc'd for C16H12N4, 261. Found, 261.

Workup

  1. customaccording to the procedure for the preparation of Example 28, part D

Sources & evidence

ORD record
ord-65a3fde260574a59a1af7bf560a95f3a
Source dataset
uspto-grants-2015_08
Patent number
US09107916B2

Reaction notes

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