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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 514478Generated: October 30, 2026

HCID 69315203, compound → HCID 86725598, compound

https://huagongshe.com/reaction/514478

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 69315203HCID 69315203—
ReactantHCID 178510213HCID 178510213—
ProductHCID 86725598HCID 86725598—

Reaction Steps

The title compound was prepared from 2-(5-hydroxy-1H-pyrazol-1-yl)pyridine-4-carbonitrile and (4-chloro-2-propan-2-yloxyphenyl)methanol according to the procedure for the preparation of Example 39, part C. 1H NMR (400 MHz, DMSO-d6): δ 1.34 (6H, d, J=6.0 Hz), 4.56-4.62 (1H, m), 5.21 (2H, s), 5.77 (1H, d, J=1.6 Hz), 6.90 (1H, d, J=1.2 Hz), 6.93 (1H, dd, J=1.6 Hz, 8.0 Hz), 7.34 (1H, d, J=8.0 Hz), 7.39 (1H, dd, J=1.2 Hz, 5.2 Hz), 7.57 (1H, d, J=1.6 Hz), 8.04 (1H, s), 8.70 (1H, d, J=4.8 Hz). [M+H] Calc'd for C19H17ClN4O2, 369. Found, 369.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09107916B2
Source datasetuspto-grants-2015_08
ORD IDord-e3411a94c31b4ce6994f2d4e826264fc
Source noteuspto-grants-2015_08