HCID 86725653, compound → HCID 86725652, compound

HRID 514548Notes

Reaction equation

HRID 514548 reaction equation
[OH:1][C:2]1[N:6]([C:7]2[CH:12]=[C:11]([C:13]#[N:14])[CH:10]=[CH:9][N:8]=2)[N:5]=[CH:4][CH:3]=1.[Cl:15][C:16]1[CH:21]=[C:20]([CH:22]2[CH2:24][CH2:23]2)[CH:19]=[CH:18][C:17]=1[CH2:25]O>>[Cl:15][C:16]1[CH:21]=[C:20]([CH:22]2[CH2:24][CH2:23]2)[CH:19]=[CH:18][C:17]=1[CH2:25][O:1][C:2]1[N:6]([C:7]2[CH:12]=[C:11]([C:13]#[N:14])[CH:10]=[CH:9][N:8]=2)[N:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 86725653HCID 86725653, compoundHCID 178510213HCID 178510213, compound

Product 1

HCID 86725652HCID 86725652, compound

Procedure

The title compound was prepared from 2-(5-hydroxy-1H-pyrazol-1-yl)pyridine-4-carbonitrile and (2-chloro-4-cyclopropylphenyl)methanol according to the procedure for the preparation of Example 39, part C. [M+H] Calc'd for C19H15ClN4O, 351. Found, 351.

Sources & evidence

ORD record
ord-74f5b137d9f6447d9859ee9e58cf58d4
Source dataset
uspto-grants-2015_08
Patent number
US09107916B2

Reaction notes

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