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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 514554Generated: October 29, 2026

HCID 84652366, compound → HCID 86725660, compound

https://huagongshe.com/reaction/514554

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 84652366HCID 84652366—
ReactantHCID 178510213HCID 178510213—
ProductHCID 86725660HCID 86725660—

Reaction Steps

The title compound was prepared from 2-(5-hydroxy-1H-pyrazol-1-yl)pyridine-4-carbonitrile and (4-cyclopropyl-3-fluorophenyl)methanol according to the procedure for the preparation of Example 39, part C. 1H NMR (400 MHz, CDCl3): δ 0.71-0.75 (2H, m), 0.96-1.02 (2H, m), 2.06-2.10 (1H, m), 5.17 (2H, s), 5.72 (1H, d, J=1.6 Hz), 6.88-6.92 (1H, m), 7.07-7.10 (2H, m), 7.40 (1H, dd, J=1.6 Hz, 5.2 Hz), 7.55 (1H, d, J=2.0 Hz), 8.02 (1H, s), 8.70 (1H, d, J=5.2 Hz). [M+H] Calc'd for C19H15FN4O, 335. Found, 335.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09107916B2
Source datasetuspto-grants-2015_08
ORD IDord-bef2ae1dabb146d6980cc2f0540b7f53
Source noteuspto-grants-2015_08