Ethyl (3-chlorobenzoyl)acetate → HCID 178510211, compound

HRID 514563Notes

Reaction equation

HRID 514563 reaction equation
[NH:1]([C:3]1[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=1)[NH2:2].[Cl:11][C:12]1[CH:13]=[C:14]([C:18](=O)[CH2:19][C:20](OCC)=[O:21])[CH:15]=[CH:16][CH:17]=1>>[Cl:11][C:12]1[CH:13]=[C:14]([C:18]2[CH:19]=[C:20]([OH:21])[N:1]([C:3]3[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=3)[N:2]=2)[CH:15]=[CH:16][CH:17]=1

Participants

3

Reactant 2

HCID 2757831Ethyl (3-chlorobenzoyl)acetateHCID 201187142-Hydrazinylpyridine-4-carbonitrile

Product 1

HCID 178510211HCID 178510211, compoundYield 53%

Procedure

The title compound was prepared in 53% yield from 2-hydrazinylpyridine-4-carbonitrile (PREPARATION 2) and ethyl 3-(3-chlorophenyl)-3-oxopropanoate according to the procedure for the preparation of Example 158, part A.

Sources & evidence

ORD record
ord-db6af07c184a475894e341e741528b60
Source dataset
uspto-grants-2015_08
Patent number
US09107916B2

Reaction notes

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