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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 514573Generated: October 25, 2026

(4-Chlorophenyl)acetic acid → Ethyl 4-(4-chlorophenyl)-3-oxobutanoate

https://huagongshe.com/reaction/514573

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Chlorophenyl)acetic acidHCID 15880—
Reactant2,2-Dimethyl-1,3-dioxane-4,6-dioneHCID 16249—
ProductEthyl 4-(4-chlorophenyl)-3-oxobutanoateHCID 1084766343%

Reaction Steps

The title compound was prepared in 43% yield from 2-(4-chlorophenyl)acetic acid and 2,2-dimethyl-1,3-dioxane-4,6-dione according to the procedure for the preparation of Example 162, part A.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09107916B2
Source datasetuspto-grants-2015_08
ORD IDord-36dec81ae7bd410bb190e8e85b29fc9e
Source noteuspto-grants-2015_08