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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 514580Generated: October 28, 2026

Potassium methyl malonate → Methyl 4-(3,5-dichlorophenyl)-3-oxobutanoate

https://huagongshe.com/reaction/514580

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium methyl malonateHCID 2724687—
Reactant2-(3,5-Dichlorophenyl)acetic acidHCID 6452487—
ProductMethyl 4-(3,5-dichlorophenyl)-3-oxobutanoateHCID 8672568378%

Reaction Steps

The title compound was prepared in 78% yield from 2-(3,5-dichlorophenyl)acetic acid and 3-methoxy-3-oxopropanoic acid potassium salt according to the procedure for the preparation of Example 170, part A.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09107916B2
Source datasetuspto-grants-2015_08
ORD IDord-590d9d0d02094a8bbca65c9de8cbed36
Source noteuspto-grants-2015_08