2-Hydrazinylpyridine-4-carbonitrile → HCID 178427846, compound

HRID 514583Notes

Reaction equation

HRID 514583 reaction equation
[NH:1]([C:3]1[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=1)[NH2:2].[F:11][C:12]1[CH:17]=[CH:16][C:15]([CH2:18][C:19](=O)[CH2:20][C:21](OC)=[O:22])=[C:14]([CH3:26])[CH:13]=1>>[F:11][C:12]1[CH:17]=[CH:16][C:15]([CH2:18][C:19]2[CH:20]=[C:21]([OH:22])[N:1]([C:3]3[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][N:4]=3)[N:2]=2)=[C:14]([CH3:26])[CH:13]=1

Participants

3

Reactant 2

HCID 201187142-Hydrazinylpyridine-4-carbonitrileHCID 86725685Methyl 4-(4-fluoro-2-methylphenyl)-3-oxobutanoate

Product 1

HCID 178427846HCID 178427846, compound

Procedure

The title compound was prepared from 2-hydrazinylpyridine-4-carbonitrile (PREPARATION 2) and methyl 4-(4-fluoro-2-methylphenyl)-3-oxobutanoate according to the procedure for the preparation of Example 158, part A.

Sources & evidence

ORD record
ord-256b0bb907024685b772d5cefb2c2bd6
Source dataset
uspto-grants-2015_08
Patent number
US09107916B2

Reaction notes

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