HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-[(Propan-2-ylsulfonyl)methyl]anilinium chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol ethylacetate | HCID 21584252 | — |
| Reactant | N-{3-[(Propan-2-ylsulfonyl)methyl]phenyl}acetamide | HCID 70976422 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-[(Propan-2-ylsulfonyl)methyl]anilinium chloride | HCID 86729611 | — |
Reaction Steps
A solution of N-{3-[(propan-2-ylsulfonyl)methyl]phenyl}acetamide (5.4 g) in ethanol (29.6 mL) was treated with concentrated hydrochloric acid (35.5 mL) and refluxed for 24 hours. The reaction mixture was condensed to dryness. The title compound (3.5 g) was obtained by crystallization from ethanol/ethyl acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09108926B2 |
| Source dataset | uspto-grants-2015_08 |
| ORD ID | ord-dea0212918ad4166a6a1d503b0117750 |
| Source note | uspto-grants-2015_08 |